In November 1992, Dr. Aaron Filler conducted the first patient imaging using a an MR Neurography-configured clinical GE Signal MRI scanner.
The patient suffered from a sciatic nerve injury. The first patient image led to the discovery that the fascicle pattern inside the nerve could be seen in an image. This image also proves that the structure imaged is indeed a nerve. The image was published in the British medical journal Lancet in 1993 and received extensive world wide attention.
There are many diagnoses and treatments of nerve trauma, entrapment and RSD. Please click on any of the links below to learn more about individualized cases from the files of Dr. Filler.
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Animation: Sciatic nerve hyperintensity associated with adhesion to a site of pelvic fracture.
(A) Sciatic nerve hyperintensity associated with adhesion to a site of pelvic fracture in a patient with new onset reflex sympathetic dystrophy (RSD). The RSD symptoms resolved after nerve release surgery.
(B) Deformation in the shape of the sciatic nerve at a site of prior trauma and failed surgical exploration.
(B1) This reconstruction in the sagittal plane shows a flattened sciatic nerve with an irregular course instead of the expected straight smooth course.
(B2) In the coronal view the sciatic nerve is broad and flat. The two images together show the severe mechanical distortion of the nerve at this site of adhesion. After four years of failed intensive pain management, the symptoms were relieved by nerve release surgery.
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Animation: Marked hyperintensity of the recurrent branch.
This animation depicts severe impingement syndrome affecting the recurrent branch of the median nerve in the wrist.
A 62-year-old woman suffered severe denervation of thenar muscles with no other symptoms of carpal tunnel syndrome after casting for a wrist fracture.
The image demonstrates marked hyperintensity of the recurrent branch as it separates from the median nerve.
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Animation: Joint nerve movement.
(A) The median nerve (mn) at the wrist located near the palmar aspect of the carpal tunnel with the tendons (te) posterior to it.
(B) The median nerve is posterior to the tendon in this image. A & B are images of the same individual at the same location in the hand but, image A is obtained with the wrist in flexion and image B is obtained in extension.
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Animation: Two views of a post-operative neuroma at site of failed nerve repair.
This animation depicts two views of a post-operative neuroma at the site of a failed nerve repair in a lacerated peroneal nerve.
The use of imaging to monitor the progress of a nerve repair may allow time to correct any problems with the initial repair.
Suture repair of nerves often provides an opportunity to recover function after severe trauma. Currently the introduction of nerve tubes for the repair of severed nerves has led to a great reduction in the length of surgical operations for nerve repair and has led to improved resutls for recovery and regrowth of severed nerves.
Dr. Aaron Filler is the world’s leading expert in treatment of nerve pain. He has revolutionized nerve-pain treatment by inventing several new technologies. One such technology, MR Neurography, enables doctors to use an MRI scanner to examine nerves — previously a difficult-to-impossible tissue to see through MR imaging. Dr. Filler's research in axonal transport is leading to a whole new generation of advanced pain medications. He has developed many new “minimal access” surgery methods that allow him to treat complex nerve problems with small outpatient surgeries. He has also pioneered the use of the Open MRI scanner to do surgeries and other therapies with the ultra-high precision and safety of the magnetic resonance imaging. Click here to learn more. Click here to learn about NerveMed and the Institute for Nerve Medicine, the medical practice that powers the information found on NerveMed.

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Do You Really Need Back Surgery? by Dr. Aaron G. Filler, MD PhD, is a best-selling paperback every sufferer of spine and nerve pain should read. Written in everyday language, the book is a must-read.
NerveMed is a free online resource dedicated to helping patients worldwide with information about spine and nerve health issues. NerveMed is powered by the Institute for Nerve Medicine in Santa Monica, California, home to Dr. Aaron G. Filler, MD PhD, a leading neurosurgeon specializing in minimally invasive treatments for spine and nerve issues. Click here to learn more.
Dr. Aaron Filler is the world’s leading expert in treatment of nerve and spine pain, having revolutionized treatments by inventing several new technologies, including MR Neurography. Dr. Filler has also pioneered minimal-access surgery methods to treat complex nerve and spine problems with outpatient surgeries. Click here to learn more.